Elfolate and Elfolate Plus contain L-methylfolate which is used to treat and prevent low levels of folate in the body. Folate is a B-vitamin naturally found in some foods. It is required by the body to form healthy cells. Elfolate is Aventura Pharmaceuticals' brand of L-methyltetrahydrofolate. It is a medical food, manufactured to pharmaceutical standards, more stringent than what the FDA requires. Our "super pure" patented active pharmaceutical ingredient is sourced in Europe, and manufactured in the U.S. to the highest quality standards. Every batch of finished product is tested for purity and potency, and Aventura Pharmaceuticals retains a COA (certificate of analysis) for each batch. Elfolate is recommended with prescription medications, to provide a nutritional supplement often helpful in patients with depression, dementia, and MTHFR mutations.