Lunovuss Visual Advantage AREDS II formula is based on the AREDS II study. The AREDS formula, which was published in 2001, resulted in a 25 percent reduction in the progression of AMD in the original AREDS study and this was also shown to be true in the AREDS II study with an even better result. The use of specific dosages of lutein and zeaxanthin in the AREDS II study showed further reduction of the progression of AMD even better than the first AREDS study, which did not have lutein or zeaxanthin. In the AREDS II study the beta carotene (Vitamin A) was found to decrease the absorption and the efficacy of lutein and zeaxanthin. Therefore, Beta carotene should not be used and lutein and zeaxanthin should take its place resulting in an even better reduction of the progression of AMD. The AREDS II study showed that a lower dose of zinc at 25mg was just as efficient as a dose of zinc at 80mg. Therefore we have included the lower dose zinc in our formula which will also help to offset the stomach irritation many patients have felt while taking an eye supplement. Lunovuss Visual Advantage is specially formulated in the United States by an FDA inspected and GMP compliant facility. We utilize todays latest medical technology to engineer the finest pharmaceutical grade supplements available to the consumer. We adhere to rigorous testing to ensure every raw ingredient that is used to make each supplement meets the highest standard. We know the importance of choosing the right manufacturer when it comes to your vision and take great pride in every product we manufacture.