Naturopathica Gastro Health Daily's unique formulation contains the Big 3 probiotics, these clinically researched species work together to provide 3 lines of defense for your gut to help: restore the balance of bacteria, relieve digestive upsets and assist in your overall wellbeing. Gastro Health does not require refrigeration and proprietary technology ensures the probiotics in Gastro Health are potent and delivered live, even at room temperatures.